2型糖尿病（T2DM）的早期诊断对于及时的治疗干预措施和生活方式改变至关重要。随着医学成像数据在许多患者群体中变得更广泛可用，我们试图研究是否可以在表格学习分类器模型中利用图像衍生的表型数据来预测T2DM的发病率，而无需使用侵入性血液实验室测量。我们表明，使用图像衍生表型的神经网络和决策树模型都可以预测患者T2DM状态的召回评分高达87.6％。我们还提出了与“ Syntha1c编码器”相同的结构的新颖使用，这些结构能够输出模仿血液血红蛋白A1C经验实验室测量值的可解释值。最后，我们证明了T2DM风险预测模型对输入矢量成分中小扰动的敏感性可用于预测从以前看不见的患者人群中取样的协变量的性能。

Current Virtual Reality (VR) environments lack the rich haptic signals that humans experience during real-life interactions, such as the sensation of texture during lateral movement on a surface. Adding realistic haptic textures to VR environments requires a model that generalizes to variations of a user's interaction and to the wide variety of existing textures in the world. Current methodologies for haptic texture rendering exist, but they usually develop one model per texture, resulting in low scalability. We present a deep learning-based action-conditional model for haptic texture rendering and evaluate its perceptual performance in rendering realistic texture vibrations through a multi part human user study. This model is unified over all materials and uses data from a vision-based tactile sensor (GelSight) to render the appropriate surface conditioned on the user's action in real time. For rendering texture, we use a high-bandwidth vibrotactile transducer attached to a 3D Systems Touch device. The result of our user study shows that our learning-based method creates high-frequency texture renderings with comparable or better quality than state-of-the-art methods without the need for learning a separate model per texture. Furthermore, we show that the method is capable of rendering previously unseen textures using a single GelSight image of their surface.

How can we accurately identify new memory workloads while classifying known memory workloads? Verifying DRAM (Dynamic Random Access Memory) using various workloads is an important task to guarantee the quality of DRAM. A crucial component in the process is open-set recognition which aims to detect new workloads not seen in the training phase. Despite its importance, however, existing open-set recognition methods are unsatisfactory in terms of accuracy since they fail to exploit the characteristics of workload sequences. In this paper, we propose Acorn, an accurate open-set recognition method capturing the characteristics of workload sequences. Acorn extracts two types of feature vectors to capture sequential patterns and spatial locality patterns in memory access. Acorn then uses the feature vectors to accurately classify a subsequence into one of the known classes or identify it as the unknown class. Experiments show that Acorn achieves state-of-the-art accuracy, giving up to 37% points higher unknown class detection accuracy while achieving comparable known class classification accuracy than existing methods.

Robotics software is pushing the limits of software engineering practice. The 3rd International Workshop on Robotics Software Engineering held a panel on "the best practices for robotic software engineering". This article shares the key takeaways that emerged from the discussion among the panelists and the workshop, ranging from architecting practices at the NASA/Caltech Jet Propulsion Laboratory, model-driven development at Bosch, development and testing of autonomous driving systems at Waymo, and testing of robotics software at XITASO. Researchers and practitioners can build on the contents of this paper to gain a fresh perspective on their activities and focus on the most pressing practices and challenges in developing robotics software today.

Everting, soft growing vine robots benefit from reduced friction with their environment, which allows them to navigate challenging terrain. Vine robots can use air pouches attached to their sides for lateral steering. However, when all pouches are serially connected, the whole robot can only perform one constant curvature in free space. It must contact the environment to navigate through obstacles along paths with multiple turns. This work presents a multi-segment vine robot that can navigate complex paths without interacting with its environment. This is achieved by a new steering method that selectively actuates each single pouch at the tip, providing high degrees of freedom with few control inputs. A small magnetic valve connects each pouch to a pressure supply line. A motorized tip mount uses an interlocking mechanism and motorized rollers on the outer material of the vine robot. As each valve passes through the tip mount, a permanent magnet inside the tip mount opens the valve so the corresponding pouch is connected to the pressure supply line at the same moment. Novel cylindrical pneumatic artificial muscles (cPAMs) are integrated into the vine robot and inflate to a cylindrical shape for improved bending characteristics compared to other state-of-the art vine robots. The motorized tip mount controls a continuous eversion speed and enables controlled retraction. A final prototype was able to repeatably grow into different shapes and hold these shapes. We predict the path using a model that assumes a piecewise constant curvature along the outside of the multi-segment vine robot. The proposed multi-segment steering method can be extended to other soft continuum robot designs.

We present a method for controlling a swarm using its spectral decomposition -- that is, by describing the set of trajectories of a swarm in terms of a spatial distribution throughout the operational domain -- guaranteeing scale invariance with respect to the number of agents both for computation and for the operator tasked with controlling the swarm. We use ergodic control, decentralized across the network, for implementation. In the DARPA OFFSET program field setting, we test this interface design for the operator using the STOMP interface -- the same interface used by Raytheon BBN throughout the duration of the OFFSET program. In these tests, we demonstrate that our approach is scale-invariant -- the user specification does not depend on the number of agents; it is persistent -- the specification remains active until the user specifies a new command; and it is real-time -- the user can interact with and interrupt the swarm at any time. Moreover, we show that the spectral/ergodic specification of swarm behavior degrades gracefully as the number of agents goes down, enabling the operator to maintain the same approach as agents become disabled or are added to the network. We demonstrate the scale-invariance and dynamic response of our system in a field relevant simulator on a variety of tactical scenarios with up to 50 agents. We also demonstrate the dynamic response of our system in the field with a smaller team of agents. Lastly, we make the code for our system available.

The cone-beam computed tomography (CBCT) provides 3D volumetric imaging of a target with low radiation dose and cost compared with conventional computed tomography, and it is widely used in the detection of paranasal sinus disease. However, it lacks the sensitivity to detect soft tissue lesions owing to reconstruction constraints. Consequently, only physicians with expertise in CBCT reading can distinguish between inherent artifacts or noise and diseases, restricting the use of this imaging modality. The development of artificial intelligence (AI)-based computer-aided diagnosis methods for CBCT to overcome the shortage of experienced physicians has attracted substantial attention. However, advanced AI-based diagnosis addressing intrinsic noise in CBCT has not been devised, discouraging the practical use of AI solutions for CBCT. To address this issue, we propose an AI-based computer-aided diagnosis method using CBCT with a denoising module. This module is implemented before diagnosis to reconstruct the internal ground-truth full-dose scan corresponding to an input CBCT image and thereby improve the diagnostic performance. The external validation results for the unified diagnosis of sinus fungal ball, chronic rhinosinusitis, and normal cases show that the proposed method improves the micro-, macro-average AUC, and accuracy by 7.4, 5.6, and 9.6% (from 86.2, 87.0, and 73.4 to 93.6, 92.6, and 83.0%), respectively, compared with a baseline while improving human diagnosis accuracy by 11% (from 71.7 to 83.0%), demonstrating technical differentiation and clinical effectiveness. This pioneering study on AI-based diagnosis using CBCT indicates denoising can improve diagnostic performance and reader interpretability in images from the sinonasal area, thereby providing a new approach and direction to radiographic image reconstruction regarding the development of AI-based diagnostic solutions.

When comparing approximate Gaussian process (GP) models, it can be helpful to be able to generate data from any GP. If we are interested in how approximate methods perform at scale, we may wish to generate very large synthetic datasets to evaluate them. Na\"{i}vely doing so would cost \(\mathcal{O}(n^3)\) flops and \(\mathcal{O}(n^2)\) memory to generate a size \(n\) sample. We demonstrate how to scale such data generation to large \(n\) whilst still providing guarantees that, with high probability, the sample is indistinguishable from a sample from the desired GP.

Effective force modulation during tissue manipulation is important for ensuring safe robot-assisted minimally invasive surgery (RMIS). Strict requirements for in-vivo distal force sensing have led to prior sensor designs that trade off ease of manufacture and integration against force measurement accuracy along the tool axis. These limitations have made collecting high-quality 3-degree-of-freedom (3-DoF) bimanual force data in RMIS inaccessible to researchers. We present a modular and manufacturable 3-DoF force sensor that integrates easily with an existing RMIS tool. We achieve this by relaxing biocompatibility and sterilizability requirements while utilizing commercial load cells and common electromechanical fabrication techniques. The sensor has a range of +-5 N axially and +-3 N laterally with average root mean square errors(RMSEs) of below 0.15 N in all directions. During teleoperated mock tissue manipulation tasks, a pair of jaw-mounted sensors achieved average RMSEs of below 0.15 N in all directions. For grip force, it achieved an RMSE of 0.156 N. The sensor has sufficient accuracy within the range of forces found in delicate manipulation tasks, with potential use in bimanual haptic feedback and robotic force control. As an open-source design, the sensors can be adapted to suit additional robotic applications outside of RMIS.

Learning from demonstration (LfD) is a proven technique to teach robots new skills. Data quality and quantity play a critical role in LfD trained model performance. In this paper we analyze the effect of enhancing an existing teleoperation data collection system with real-time haptic feedback; we observe improvements in the collected data throughput and its quality for model training. Our experiment testbed was a mobile manipulator robot that opened doors with latch handles. Evaluation of teleoperated data collection on eight real world conference room doors found that adding the haptic feedback improved the data throughput by 6%. We additionally used the collected data to train six image-based deep imitation learning models, three with haptic feedback and three without it. These models were used to implement autonomous door-opening with the same type of robot used during data collection. Our results show that a policy from a behavior cloning model trained with haptic data performed on average 11% better than its counterpart with no haptic feedback data, indicating that haptic feedback resulted in collection of a higher quality dataset.